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School of Molecular & Biomedical Science |
Rhizopus sp.The genus Rhizopus is characterized by the presence of stolons and pigmented rhizoids, the formation of sporangiophores singly or in groups from nodes directly above the rhizoids, and apophysate, columellate, multi-spored, generally globose sporangia. After spore release the apophyses and columella often collapse to form an umbrella-like structure. Sporangiospores are globose to ovoid, one-celled, hyaline to brown and striate in many species. Colonies are fast growing and cover an agar surface with a dense cottony growth that is at first white becoming grey or yellowish brown with sporulation.
MIC data is limited. Antifungal susceptibility testing of individual strains is recommended.
Clinical significance:Rhizopus oryzae (=R. arrhizus) is the most common causative agent of zygomycosis, accounting for some 60% of the reported culture positive cases, and nearly 90% of the rhinocerebral forms of infection. R. oryzae has a world-wide distribution with a high prevalence in tropical and subtropical regions. It has been isolated from many substrates, including a wide variety of soils, decaying vegetation, foodstuffs, and animal and bird dung. R. oryzae is often used in the production of fermented foods and alcoholic beverages in Indonesia, China and Japan. However, it also produces the ergot alkaloid agroclavine which is toxic to humans and animals. Rhizopus oryzae description
Differentiation of pathogenic Rhizopus microsporus group isolates.
Mycosis: ZygomycosisFurther reading:Domsch, K.H., W. Gams, and T.H. Anderson. 1980. Compendium of soil fungi. Volume 1. Academic Press, London, UK. Ellis, D.H. 1997. Zygomycetes. Chapter 16 In Topley and Wilson's Microbiology and Microbial Infections. 9th edition Edward Arnold London pp247-277.
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